#immunology

Researchers at MUSC report that modified mesenchymal stem cells reversed new-onset type 1 diabetes in a mouse model by combining immune regulation with anti-inflammatory protection.

Doctors in Wisconsin reported that a woman’s myxofibrosarcoma disappeared within weeks of a diagnostic biopsy, a rare outcome that researchers think may reflect an immune response triggered by the procedure

Mammalian meat allergy is a rare example of a food allergy triggered by an environmental event, with tick bites capable of setting off a reaction to red meat.

A study in Immunity points to malfunctioning natural killer cells, not macrophages alone, as a key driver of mevalonate kinase deficiency, opening a possible path toward JAK inhibitor treatment.

Researchers report an HIV vaccine design that steered immune responses toward a conserved region of the virus and produced broadly neutralizing antibodies in macaques.

Researchers report previously unrecognized immune surveillance structures in hair follicles, suggesting the skin may monitor microbes and environmental exposure through more specialized local gateways than previously

A Julius Maximilian University of Wurzburg study reports that a rare type of T cell can trigger signaling that amplifies inflammation and contributes to liver fibrosis.

Researchers tracking glioblastoma-like tumors in living mouse brains found that microglia initially increase surveillance activity in far-away tissue, then lose that response as invasion intensifies

Researchers at the Josep Carreras Leukaemia Research Institute report a biological off switch in diffuse large B cell lymphoma, opening potential routes for diagnosis and treatment.

A Nature study from Washington University in St. Louis found that mRNA cancer vaccines can still trigger strong anti-tumor responses in mice even when a dendritic cell subtype long thought essential is missing.

A first-in-human trial at UPMC and the University of Pittsburgh suggests some living donor liver transplant recipients can be safely weaned off immunosuppressive drugs after donor-derived immune cell priming.

A Nature Medicine study from researchers at Aarhus University finds that the menstrual cycle systematically shifts nearly 200 blood proteins, pointing to wider effects on immunity and disease biology than previously seen

A Rockefeller University-led study describes a gene-editing approach that reprograms a small number of stem cells so the immune system can produce long-lasting therapeutic proteins, including protective antibodies.

Bain Capital has officially launched Beeline Medicines with five assets from Bristol Myers Squibb, creating a new biotech centered on shelved immunology drugs.

Researchers say the naturally occurring immunopeptide PEPITEM reduced joint swelling and inflammation in early-stage inflammatory arthritis to a degree comparable with current standard care.

Researchers have developed a technique that measures RNA and proteins together in single cells, offering a more complete view of immune signaling.

A randomized phase 3 study reports that benralizumab significantly reduced the risk of first flare in patients with FIP1L1::PDGFRA-negative hypereosinophilic syndrome while showing a safety profile consistent with prior用

Researchers argue that endometriosis should be understood as a condition that drives immune disruption across the body, widening the frame beyond lesions in the pelvis alone.

Biogen says its anti-BDCA2 antibody litifilimab improved skin lesions after 24 weeks in a Phase 2 lupus study, giving the company a clinical win for a program it hopes will anchor its immunology pipeline.

A 900,000-person study published in Nature reveals how age, sex, season, smoking, and genetics shape the viral loads of seven DNA viruses that persist in the human body across a lifetime.