#immunology

Penn Engineers have developed a new lipid nanoparticle design that steers mRNA vaccines directly to lymph nodes while dramatically reducing off-target delivery, a breakthrough that could improve vaccine efficacy and safety across a wide range of applications.

Scientists have developed DoriVac, a DNA nanostructure vaccine platform producing stronger and more durable immune responses than mRNA vaccines in early studies, with applications targeting HIV, Ebola, and COVID-19.

A new study reveals that the STING-NF-kB signaling pathway acts as a natural barrier preventing influenza viruses from spilling over from animals to humans.

Imperial College London researchers uncover how estrogen amplifies allergic lung inflammation through IL-33 and EGFR signaling in female airways.

New research reveals how estrogen amplifies IL-33 signaling in airways, explaining why women experience more severe asthma than men after puberty.

Scientists discover how premalignant lung cells suppress immune surveillance, revealing potential targets for intercepting cancer before it fully develops.