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Immune Evasion Mechanism Found in Pre-Cancer Lung Lesions
Key Takeaways
- Pre-cancerous lung lesions already deploy immune evasion strategies typically seen only in advanced established tumors
- Cells upregulate PD-L1 and downregulate MHC class I molecules to hide from immune surveillance before cancer forms
- Understanding how some lesions progress while others regress could enable cancer interception at the earliest treatable stage
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DT Editorial Team··5 min read·via medicalxpress.com