#genomics

一项新发表在《Science》上的研究报告称，单细胞多组学分析识别出了唐氏综合征发育中新皮层中失调的分子和基因调控机制。

研究人员分析了数百份样本，识别出与胃癌相关的口腔和肠道微生物特征，表明基于唾液的筛查或许有助于更早发现疾病，并阐明口腔细菌如何帮助……

研究人员表示，在基因组的非编码区域中发现了婴儿糖尿病新的遗传致病原因，而以往研究常常忽略这些区域。

A new Nature Medicine report describes the detection of mpox clade IIb in the Republic of the Congo alongside clades Ia and Ib, highlighting a more complex outbreak picture and the need for stronger surveillance and case

一项聚焦秘鲁城市居民的新基因组研究指出了全球健康研究中的更大问题：拉丁美洲人群在遗传流行病学中仍然代表性不足。

一篇新近列入《Science》的论文关注南美洲主要疟疾传播媒介按蚊（Anopheles darlingi）的群体基因组学，凸显基因组学在追踪和控制蚊媒疾病中的日益重要作用。

Optical genome mapping detects previously missed genetic variants in nearly 20% of acute leukemia patients, potentially changing treatment plans.

A mysterious RNA molecule found in breast cancer tissue has led researchers to uncover approximately 260,000 cancer-specific small RNAs across 32 tumor types. These orphan non-coding RNAs act as molecular barcodes for cancer identity and could transform how doctors detect and monitor the disease.