
Foamy immune cells may help explain why some multiple sclerosis cases worsen faster
A Nature Neuroscience study links severe multiple sclerosis progression to fat-laden microglia that appear overwhelmed by myelin cleanup, pointing to possible biomarkers and treatment targets.
- Researchers found large numbers of fat-laden microglia in rapidly progressing MS tissue.
- Patients with more foamy microglia more often had severe disease courses.


