#multiple myeloma

All articles tagged with "multiple myeloma"

A CAR-T result in high-risk smoldering multiple myeloma points to a more aggressive early-treatment debate

A single infusion of ciltacabtagene autoleucel reportedly produced a 100% MRD-negativity rate in patients with high-risk smoldering multiple myeloma, an outcome that could intensify discussion around how early advanced c

Key Takeaways

Medical Xpress reports that a single infusion of ciltacabtagene autoleucel led to a 100% MRD-negativity rate in the studied group.
The reported patients had high-risk smoldering multiple myeloma.

DT Editorial Team·Apr 20, 2026·via medicalxpress.com

European drug panel backs four new medicines and a new form of Sanofi’s Sarclisa

The European Medicines Agency’s human medicines committee has recommended four new drugs and a subcutaneous form of Sanofi’s multiple myeloma treatment Sarclisa, setting up a new set of regulatory decisions in Europe.

Key Takeaways

CHMP recommended four new drugs and a subcutaneous form of Sanofi’s Sarclisa.
The decision is an important scientific milestone ahead of final European Commission action.

DT Editorial Team·Mar 29, 2026·via endpoints.news

Phase 1 Study Suggests In Vivo CAR-T Manufacturing Could Shorten the Path to Myeloma Treatment

A small phase 1 study in relapsed or refractory multiple myeloma reports that anti-BCMA CAR-T cells can be generated inside the body after a single infusion, potentially bypassing several steps that usually slow access.

Key Takeaways

A phase 1 study tested an anti-BCMA CAR-T approach generated inside the body rather than manufactured outside it.
Five heavily pretreated patients received a single intravenous infusion without leukapheresis, ex vivo manufacturing, or lymphodepleting chemotherapy.

DT Editorial Team·Mar 27, 2026·via nature.com