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All articles tagged with "cancer-research"

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Experimental pancreatic cancer pill shows major survival gain

Daraxonrasib was tested in 500 patients with metastatic pancreatic cancer.
Researchers reported average survival of 13.2 months versus 6.7 months on chemotherapy.
The daily pill was also described as causing fewer side effects than standard chemotherapy.

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DT Editorial Team·Jun 2, 2026·via newscientist.com

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Children's brain tumors may spread faster when microglia build invasion-friendly scaffolding

Tumor-linked microglia may help deadly childhood brain cancers spread

Microglia exposed to DMG cells produced high levels of fibronectin.
Blocking fibronectin reduced tumor-cell invasiveness in lab experiments.
Higher fibronectin levels were associated with poorer prognosis across patient cohorts.

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DT Editorial Team·Jun 1, 2026·via medicalxpress.com

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Scientists identify metabolic target to overcome chemotherapy resistance in ovarian cancer

Ovarian cancer study points to a metabolic weak spot in chemo resistance

Researchers linked chemotherapy resistance in some ovarian cancers to a metabolic pathway involving alpha-ketoglutarate.
The study identified TMLHE as an enzyme connected to tumor DNA repair capacity.
The findings suggest an existing drug may help weaken resistance when paired with chemotherapy.

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DT Editorial Team·May 28, 2026·via medicalxpress.com

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Researchers Link Leukemia Stem Cells to AML Treatment Failure

Researchers at DKFZ and HI-STEM say they identified a key mechanism behind AML treatment failure.
The finding links leukemia stem cells to resistance.
The report says the work opens new avenues to overcome resistance.

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DT Editorial Team·May 8, 2026·via medicalxpress.com

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Study links tumor splicing burden to treatment response in metastatic renal cell carcinoma

Researchers reported a significant correlation between splicing burden and treatment response.
The study focuses on metastatic renal cell carcinoma.
The result points to a possible new biomarker direction in precision oncology.

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DT Editorial Team·May 5, 2026·via medicalxpress.com

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DT Editorial Team·Apr 30, 2026·via medicalxpress.com

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DT Editorial Team·Apr 30, 2026·via medicalxpress.com

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DT Editorial Team·Apr 24, 2026·via statnews.com

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DT Editorial Team·Apr 22, 2026·via medicalxpress.com

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DT Editorial Team·Apr 21, 2026·via medicalxpress.com

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DT Editorial Team·Apr 21, 2026·via medicalxpress.com

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DT Editorial Team·Apr 21, 2026·via medicalxpress.com

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DT Editorial Team·Apr 20, 2026·via statnews.com

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DT Editorial Team·Apr 18, 2026·via medicalxpress.com

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DT Editorial Team·Apr 16, 2026·via medicalxpress.com

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DT Editorial Team·Apr 14, 2026·via medicalxpress.com

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DT Editorial Team·Apr 11, 2026·via medicalxpress.com

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DT Editorial Team·Mar 23, 2026·via technologyreview.com

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DT Editorial Team·Mar 15, 2026·3 min read·via sciencedaily.com

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DT Editorial Team·Mar 2, 2026·4 min read·via sciencedaily.com

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Researchers found a new way to strip drug-resistant tumors of a key DNA repair advantage

Researchers identified UNI418 as a molecule that reduces key DNA repair proteins in cancer cells.
The compound appears to work by activating the Cul4A ubiquitin ligase degradation pathway.
The finding could point to a new strategy for overcoming resistance to DNA-damage-based cancer therapies.

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Tumor-on-a-chip study spotlights why pancreatic cancer is so hard to treat

A new tumor-on-a-chip model focuses on pancreatic cancer’s interaction with scar tissue
The work targets a core reason pancreatic tumors are difficult to treat
The platform could help researchers study treatment resistance in a more realistic setting

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Heart’s beat may help it beat cancer, mouse research suggests

Mouse Study Suggests the Beating Heart May Be Naturally Hostile to Cancer

Candidate metadata says mouse research suggests the beating heart may help explain why heart cancers are rare.
The proposed mechanism is constant pressure creating an environment hostile to cancers.
The finding is early and should be treated as a theory rather than a confirmed human explanation.

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Glioblastoma Study Identifies Molecule Linked to Better Responses and Immune Memory

Researchers studying exceptional glioblastoma responders found higher levels of miR-181d in their tumors.
The molecule appears to suppress RAD51, a protein cancer cells use to repair treatment-induced DNA damage.
In preclinical models, restoring miR-181d before radiation also appeared to improve long-term immune recognition of the tumor.

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Wildfire Smoke Study Links Exposure to Higher Cancer Risk Signals

Wildfire smoke exposure was associated with increased risk of several cancers.
The supplied source supports association, not causation.
The finding could affect long-term public health planning in smoke-prone regions.

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Researchers Identify Protective Switch in Common Blood Cancer

Researchers report a biological off switch in diffuse large B cell lymphoma.
The study was published in The Journal of Immunology.
The finding may support future diagnostic and treatment research.

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Researchers Report a New Route Toward Neuroblastoma Drugs by Blocking a Key Protein Partnership

Researchers at Linköping University say they can prevent two important cancer-related proteins from collaborating.
The result is framed as opening a path toward future medications for neuroblastoma.
The work appears to be an early-stage research advance rather than a finished treatment.

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AACR 2026: More strong data for Revolution Medicines’ KRAS drug

Revolution Medicines highlights new KRAS pill data at AACR 2026

Revolution Medicines highlighted new AACR 2026 data for a KRAS-targeting pancreatic cancer pill.
The company framed the results as unusually strong, signaling confidence in the program.
The supplied source does not include detailed efficacy or safety figures, so the update remains an early signal rather than a final verdict.

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Researchers find mRNA cancer vaccines can still rally tumor-killing immunity without a presumed key cell

Researchers tested mRNA cancer vaccination in mice.
Strong anti-tumor responses persisted even without a dendritic-cell subtype thought essential.
The study points to an alternate dendritic-cell pathway that could inform vaccine design.

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Researchers Identify Protein Linked to Fast Spread of Triple-Negative Breast Cancer

Researchers identified a protein tied to the spread of triple-negative breast cancer.
The report frames the protein as central to metastatic behavior.
The supplied details are limited, so broader clinical claims are not supported yet.

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New RNA Target Could Strengthen EGFR Drug Strategies Against Glioblastoma

Researchers linked a novel long non-coding RNA to glioblastoma cell growth.
The RNA acts alongside EGFR amplification, a change seen in more than half of glioblastoma tumors.
The finding could help EGFR drugs work better if validated in follow-up studies.

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Meta-Analysis Finds No Higher Respiratory Cancer Risk From Asbestos-Free Talc Exposure at Work

Researchers reported no increased respiratory cancer risk from occupational exposure to asbestos-free talc.
The study was a systematic review and meta-analysis, synthesizing evidence rather than relying on one dataset.
The finding is narrow but important because it separates asbestos-free talc from talc contaminated with asbestos.

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Can quantum computers now solve health care problems? We’ll soon find out.

Quantum Computers Race for $5M Healthcare Prize at Oxford

Six finalist teams compete for a $5M Wellcome Leap prize to demonstrate quantum advantage in real healthcare problems classical computers cannot solve
All six teams independently developed hybrid quantum-classical approaches, with classical algorithms improving as a byproduct of quantum hardware constraints
Problems being attacked include light-activated cancer drug simulation, genomic diversity mapping, and cancer origin identification from tumor genome data

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Sweet Cherry Compounds Show Promise in Slowing Aggressive Breast Cancer Spread, Texas A&M Study Discovers (via vetmed.tamu.edu)

Cherry Compounds Show Promise Against Aggressive Breast Cancer

Mouse study finds dark sweet cherry extracts slow triple-negative breast cancer growth via anthocyanin compounds
Compounds appeared to inhibit tumor signaling, reduce angiogenesis, and trigger cancer cell death in animal models
Effective concentrations far exceed what whole fruit consumption could achieve — human trials are years away

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Scientists reveal why a popular anti-aging compound may also fuel cancer

Anti-Aging Compound Polyamines May Also Drive Cancer Growth

Polyamines activate eIF5A1 in healthy cells but eIF5A2 in cancer cells
The switch mechanism involves disruption of a regulatory molecule miR-6514-5p
eIF5A2 identified as potential drug target for cancer treatment

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