#biotechnology

Researchers report a way to use engineered red blood cells to ferry mRNA into the body and reprogram myeloid immune cells to attack tumors, pointing to a potential alternative to conventional CAR cell manufacturing.

Researchers at the University of Trento report an mRNA-based genome-editing approach aimed at a cystic fibrosis mutation that affects about 10% of patients and does not respond to some current drug therapies.

Utah startup Paterna Biosciences says it produced functional human sperm in the lab and used it to create apparently healthy embryos, a claim that could reshape infertility treatment if independently verified.

A University of Toronto study identifies how bacterial strains make medium-chain fatty acids, a finding that could support greener production of chemicals now largely sourced from palm kernel oil.

Researchers are working at the molecular scale to move medicine inside cells, reflecting a broader push to make treatment more precise than conventional pills.

A Rockefeller University-led study describes a gene-editing approach that reprograms a small number of stem cells so the immune system can produce long-lasting therapeutic proteins, including protective antibodies.

Researchers once saw mirror-image microbes as a frontier science project with major medical potential. Now some of the same scientists warn that the technology could pose existential biological risks.

Researchers report an enhanced CRISPR system that could support targeted delivery inside the body, with the source text citing editing efficiencies of up to 90%.

Researchers at the Manchester Institute of Biotechnology say engineering biology could provide a cheaper and more sustainable way to manufacture the HIV drug Lenacapavir.

Moderna and Merck are describing a personalized mRNA cancer treatment as a therapy rather than a vaccine, reflecting how politics and regulation are reshaping biotech language.

Researchers at Aarhus University say they have developed a microscopic DNA needle that can deliver molecules directly into cells while helping them remain active after arrival.

New attention on gene-targeting technology is widening its role beyond gene editing, with STI diagnosis emerging as a notable application area.

A research team in Spain says it kept a donated human uterus alive for a day using a custom perfusion machine, opening a new experimental path for studying implantation, uterine disease, and early pregnancy.

Rockefeller University researchers built MultiQ-IT, a mass spectrometry device that processes billions of molecules in parallel, achieving 100-fold better sensitivity and potentially transforming drug discovery.

Scientists have developed DoriVac, a DNA nanostructure vaccine platform producing stronger and more durable immune responses than mRNA vaccines in early studies, with applications targeting HIV, Ebola, and COVID-19.

Ugur Sahin and Ozlem Tureci will exit BioNTech by year-end to start a company focused on next-generation mRNA innovations.