Health

MD Anderson team identifies YAP1 as a marker of chemotherapy resistance in relapsed lung cancer

MD Anderson researchers identified YAP1 as a biomarker associated with chemotherapy resistance in relapsed lung cancer.
The report says some cancer cells express YAP1 only after treatment, helping them survive.
The finding could support future monitoring and therapy strategies aimed at resistant disease.

DT Editorial Team·May 6, 2026·via medicalxpress.com

Study Zeroes In on Honor-Driven Anxiety Across Shame-Based Cultures

Researchers introduced and validated atimiaphobia in PsyCh Journal.
The concept describes an intense fear of losing honor or being labeled shameless.
The study highlights how culture can shape how psychological distress is experienced and understood.

DT Editorial Team·May 6, 2026·via medicalxpress.com

Visa backlog could block foreign doctors from underserved U.S. communities

Hundreds of foreign doctors may have to leave the U.S. if visa waivers are not processed quickly.
The program routes physicians into underserved areas in exchange for at least three years of service.
Attorneys say a backlog has built after much faster processing in prior years.
If doctors must reenter later, employers could face a new $100,000 H-1B-related fee.

DT Editorial Team·May 6, 2026·via medicalxpress.com

CDC report finds 50 large tuberculosis outbreaks across 23 U.S. states

The CDC identified 50 large TB outbreaks involving 1,092 cases from 2017 to 2023.
Outbreak-linked cases were disproportionately U.S.-born and more often associated with substance use, homelessness and incarceration.
About one quarter of outbreak cases were found through contact tracing.
The report argues for response strategies that address social barriers to diagnosis and treatment.

DT Editorial Team·May 6, 2026·via medicalxpress.com

Large Review Finds Newer Migraine Drugs Cut Headache Days With Fewer Side Effects

A large review examined 43 studies on migraine treatment options.
Newer migraine drugs were associated with fewer headache days and fewer side effects.
The findings may improve treatment selection for chronic migraine patients.

DT Editorial Team·May 6, 2026·via medicalxpress.com

Alzheimer’s Drug Pipeline Expands Beyond Amyloid as Trials Surge

An annual report found a 35% rise in Alzheimer’s clinical trials and a 40% increase in therapies being tested since 2016.
Amyloid-targeting drugs now make up about 20% of the pipeline, down from roughly one-third in 2016.
Inflammation and immune-targeting therapies have grown to 18% of the pipeline, reflecting a broader scientific strategy.

DT Editorial Team·May 6, 2026·via medicalxpress.com

Researchers Point to a Brain-Based Index for Alzheimer’s Risk Patterns Decades Before Old Age

A report says a brain-based index may reveal Alzheimer’s risk patterns in adults as young as 30.
The supplied source text says researchers have long used health records, brain scans, and other data to seek biological markers.
The significance of the finding is its focus on much earlier stages of possible risk.
The available source material supports cautious interpretation rather than clinical conclusions.

DT Editorial Team·May 5, 2026·via medicalxpress.com

Researchers map Parkinson’s into two major forms and five subgroups

Researchers grouped Parkinson’s into two broad molecular types and five subgroups.
The study used fruit fly models with Parkinson’s-related mutations and machine-learning analysis.
The findings support a shift toward more personalized therapies instead of one-size-fits-all treatment.

DT Editorial Team·May 5, 2026·via medicalxpress.com

Study links tumor splicing burden to treatment response in metastatic renal cell carcinoma

Researchers reported a significant correlation between splicing burden and treatment response.
The study focuses on metastatic renal cell carcinoma.
The result points to a possible new biomarker direction in precision oncology.

DT Editorial Team·May 5, 2026·via medicalxpress.com

A Single Psilocybin Dose Appears to Reshape Brain Activity for Weeks

Researchers found that a high dose of psilocybin increased brain entropy during the acute experience.
The degree of entropy was linked to next-day reports of insight and emotional self-awareness.
Those reported insights forecasted improvements in well-being a month later.
The study was conducted in healthy volunteers and used multiple brain measurement techniques.

DT Editorial Team·May 5, 2026·via medicalxpress.com

GLP-1 Prescriptions Surge, but Severe Obesity Still Goes Untreated

Researchers analyzed electronic health records from nearly 20 million patients with severe obesity.
GLP-1 prescriptions grew exponentially in the study population.
The study says severe obesity still often goes untreated.
The findings coincide with a decline in bariatric surgery use.

DT Editorial Team·May 5, 2026·via medicalxpress.com

Bariatric surgery linked to sharply lower kidney failure and heart risks in chronic kidney disease study

A five-year real-world study compared bariatric surgery patients with similar CKD patients who did not have surgery.
The surgery group had lower risks of end-stage kidney disease, dialysis, cardiovascular events and death.
Researchers argue the data support considering metabolic surgery earlier in CKD care for patients with obesity.

DT Editorial Team·May 5, 2026·via medicalxpress.com

'Zombie' cells spark inflammation in severe fatty liver disease, Mayo Clinic researchers find - Mayo Clinic News Network (via newsnetwork.mayoclinic.org)

Researchers report a newly identified liver cell that may help explain common liver disease

University of Michigan researchers reported a newly identified liver cell type.
The source says the cell may protect against a common liver disease.
The finding is early but could shape future treatment research.

DT Editorial Team·May 4, 2026·via medicalxpress.com

Phage Cocktail Study Maps a Way Around Resistance in a Hard-to-Treat Lung Infection

Researchers identified how Mycobacterium abscessus escapes phage therapy.
The study showed a combination strategy that can overcome resistance pathways.
The work supports more durable phage cocktail design against drug-resistant infections.

DT Editorial Team·May 4, 2026·via medicalxpress.com

Clinical trials are key to improving medicines access in Africa (via weforum.org)

Why Africa’s Absence From Clinical Trials Matters Far Beyond Research Design

The candidate argues that Africa is missing from too much of the clinical trial system.
That underrepresentation is notable because the continent carries a large disease burden.
The gap challenges the idea that modern medical evidence is fully universal.
The issue has implications for both research quality and health equity.

DT Editorial Team·May 4, 2026·via medicalxpress.com

Food baskets for tuberculosis patients could save lives at scale in India, study finds

Researchers say food baskets for TB-affected households in India could be cost-effective.
Universal coverage was estimated to avert about 120,000 TB deaths annually.
The modeled cost per health gain was $141, below the cited $550 benchmark.
The work highlights undernutrition as a central driver of TB outcomes.

DT Editorial Team·May 4, 2026·via medicalxpress.com

Hepatitis C-Positive Donors Could Expand Access to Pancreas Transplants

Cedars-Sinai says hepatitis C-positive donors may shorten pancreas transplant wait times.
The finding could expand the effective donor pool for transplant candidates.
The broader significance is operational: faster access through revised organ-use practice.

DT Editorial Team·May 4, 2026·via medicalxpress.com

High-Intensity Intervals Lead Vascular Gains in Review of Cardiac Exercise Studies

A review of 37 studies compared exercise modalities in cardiovascular patients.
High-intensity interval exercise showed the strongest and most consistent endothelial benefits.
The findings support a larger role for interval-based training in appropriate cardiac rehabilitation settings.

DT Editorial Team·May 4, 2026·via medicalxpress.com

AI Imaging Method Spots Keratoconus Before Standard Exams Can

Researchers combined PS-OCT with AI to detect subtle corneal changes tied to early keratoconus.
The method focuses on collagen organization rather than corneal shape alone.
The approach could improve screening for patients being evaluated for refractive surgery.

DT Editorial Team·May 4, 2026·via medicalxpress.com

A Blood-Aging Signal May Help Explain Why Depression Does Not Look the Same in Everyone

Researchers linked a blood-based aging signal to cognitive and mood-related depression symptoms.
The finding was highlighted in work involving women with HIV, who face elevated depression risk.
The result points toward more specific biomarkers rather than a single universal depression test.

DT Editorial Team·May 4, 2026·via medicalxpress.com