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Hidden Neuron 'Gatekeeper' May Drive Alzheimer's Progression
Key Takeaways
- Scientists discover an endosomal clearance hub in neurons that acts as a molecular switch controlling amyloid-beta processing
- When this gatekeeper mechanism fails, toxic amyloid-beta 42 peptide accumulates and seeds the plaques driving Alzheimer's
- The finding could fundamentally alter therapeutic approaches to Alzheimer's, which affects over 55 million people worldwide
DE
DT Editorial Team··5 min read·via medicalxpress.com







