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© 2026 Developments Today. All rights reserved.

microbiome Articles | Developments Today

Fecal microbe transplantation may improve sleep in people with chronic insomnia

Gut microbiome transplant shows promise for chronic insomnia

A randomized, double-blind, placebo-controlled trial tested microbiota capsules for chronic insomnia.
The treatment group showed better sleep efficiency and less wakefulness after sleep onset after one month.
Patient-reported sleep quality also improved over a two- to six-month period compared with placebo.

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DT Editorial Team·Jul 22, 2026·via medicalxpress.com

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Breast milk gives certain gut bacteria a head start

Breast Milk Sugars May Shape the Gut for Years

Researchers say sugars in breast milk help select gut bacteria that persist through weaning.
The effect appears tied to microbes that can process both milk-derived sugars and plant fibers.
The findings strengthen the case for continuing breastfeeding as solid foods are introduced.

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DT Editorial Team·Jun 30, 2026·via medicalxpress.com

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Maternal weight may influence microbiota signaling in amniotic fluid

Study links maternal weight factors to microbiota signals in amniotic fluid

Researchers analyzed stool and amniotic fluid samples from 60 pregnant women.
Maternal overweight, obesity, gestational diabetes, and high pregnancy weight gain were associated with vesicle profiles.
The findings suggest microbial signaling may extend into the fetal environment.

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DT Editorial Team·Jun 21, 2026·via medicalxpress.com

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GLP-1s may alleviate depression through the microbiome, mouse study suggests

GLP-1 Drugs May Ease Depression via Gut Microbiome, Mouse Study Finds

Liraglutide accumulated in the intestine, not the brain, in stressed mice.
Antidepressant effects persisted in mice with GLP-1 receptors knocked out.
Depleting gut microbiota with antibiotics eliminated the antidepressant effect.
Lactobacillus delbrueckii increased significantly and produces a precursor to the endocannabinoid 2-AG.

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DT Editorial Team·Jun 10, 2026·via medicalxpress.com

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Gut microbiome patterns point to Parkinson’s risk years before diagnosis

Gut microbiome patterns point to Parkinson’s risk years before diagnosis

Nature Medicine says microbiome changes track from healthy people to at-risk and symptomatic groups.
The study suggests some individuals could be flagged years before Parkinson’s symptoms appear.
A healthy diet was inversely associated with the risk-linked microbiome alterations.

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DT Editorial Team·May 30, 2026·via nature.com

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Aerobic exercise may lessen the health effects of exposure to nanoplastics

Exercise May Blunt Some Health Damage From Nanoplastics, Zebrafish Study Suggests

Female zebrafish exposed to polystyrene nanoplastics showed ovarian, hormonal, behavioral, and microbiome disruption.
Moderate aerobic exercise lessened many of those effects during the 21-day exposure period.
Researchers linked the protective effect to gut microbial changes and improved neuroendocrine health.

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DT Editorial Team·May 20, 2026·via medicalxpress.com

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Gut microbiome study finds bacteria use reversible 'bet-hedging' to survive disruption

Researchers say gut bacteria can shift into alternative epigenetic states without changing DNA sequence.
The mechanism may help microbiomes withstand antibiotics, illness and diet changes.
The finding could help explain uneven responses to probiotics and fecal microbiota transplantation.

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DT Editorial Team·May 19, 2026·via medicalxpress.com

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What scientists found inside coral reefs could change the future of medicine

Coral reef microbes reveal a vast chemical library with medical promise

Researchers reconstructed 645 microbial genomes from Pacific coral reefs.
More than 99% of the species had not been genetically described before.
The microbes showed exceptional potential for producing natural compounds.

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DT Editorial Team·May 9, 2026·via sciencedaily.com

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Scientists discover a new way to prevent gum disease without killing good bacteria

Scientists Target Gum Disease by Disrupting Bacterial ‘Conversations’

Researchers found that disrupting AHL chemical signals in dental plaque can favor healthier bacteria.
The work suggests oral microbes above and below the gumline may be linked by shared signaling.
The approach could become an alternative to broad antimicrobial strategies if further validated.

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DT Editorial Team·May 8, 2026·via sciencedaily.com

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A common constipation drug shows surprising power to protect kidneys

Constipation Drug Shows Early Promise as a Kidney Disease Treatment

A Phase II trial involving 150 patients found lubiprostone slowed kidney function decline in moderate CKD.
Researchers linked the effect to microbiome changes that boosted spermidine production.
The result supports growing interest in the gut-kidney axis as a therapeutic target.

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DT Editorial Team·May 8, 2026·via sciencedaily.com

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Harvard scientists link gut bacteria to depression through hidden inflammation trigger

Harvard Researchers Trace a Possible Gut-to-Depression Path Through an Inflammation Trigger

Researchers identified a mechanism involving Morganella morganii and the contaminant DEA.
The altered bacterial molecule triggers immune activity and inflammatory cytokines.
The findings may open paths to diagnosis or treatment that target immune pathways.

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DT Editorial Team·Apr 25, 2026·via sciencedaily.com

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Saliva and gut microbes emerge as early warning signs for gastric cancer

Researchers found microbial signatures in oral and gut samples linked to gastric cancer.
Many enriched gut bacteria in cancer patients are typically found in the mouth.
Strain analysis suggested oral bacteria migrate into the gastrointestinal tract.
The microbial network was associated with lactic acid fermentation and a more tumor-friendly environment.

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DT Editorial Team·Apr 20, 2026·via medicalxpress.com

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A low-protein diet isn't normally associated with weight loss, but a new study might cause researchers to look at this way of eating in a different light

Mouse study links low-protein diets, gut microbes, and fat-burning tissue

A mouse study found that low protein intake can trigger fat browning through gut microbes.
Two signaling routes, involving FXR and FGF21, were highlighted.
The work suggests therapeutic possibilities but remains far from a human-ready intervention.

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DT Editorial Team·Apr 17, 2026·via refractor.io

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Gut microbial diversity and inferred capacity to produce butyrate modulate cortisol reactivity following acute stress in healthy adults (via biorxiv.org)

Gut Microbe Diversity Is Linked to Cortisol Surges During Acute Stress

University of Vienna researchers link gut bacteria diversity to cortisol spikes during acute stress
The study focuses on healthy adults rather than a clinical patient group
The finding adds to evidence that the microbiome is involved in broader physiological regulation

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DT Editorial Team·Apr 17, 2026·via medicalxpress.com

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Gut Microbiome Study Adds a New Clue to the HIV Persistence Puzzle

Karolinska Institutet researchers reported an association between gut bacteria composition and latent HIV levels
The finding concerns people receiving antiretroviral therapy
The study points to a potential new avenue for HIV persistence and cure research

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DT Editorial Team·Apr 9, 2026·via medicalxpress.com

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A close up shows a white rat with a brown head holding onto a small thread in front of a blue background.

A Mediterranean-Diet Microbe Boosted Muscle Strength in Mice

Researchers linked a specific gut bacterium to stronger muscles in people.
Feeding that microbe to mice increased their muscle strength.
The work raises the possibility of future probiotic approaches for muscle health.

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DT Editorial Team·Mar 30, 2026·via livescience.com

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Microbiome modulation in cancer immunotherapy - Nature Medicine

Gut Microbiome Transplants Boost Cancer Immunotherapy Results

Melanoma patients receiving microbiome transplants had 42% immunotherapy response rate vs 27% control
Results consistent across three independent trials with different cancer types
Could become standard adjunct to immunotherapy if confirmed in phase three trials

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DT Editorial Team·Mar 11, 2026·4 min read·via nature.com

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Your Oral Microbiome May Hold Keys to Systemic Disease

Over 700 bacterial species inhabit the human mouth, with links to cardiovascular disease and cancer
Oral bacteria have been found in atherosclerotic plaques and colorectal tumors
Gum disease treatment reduces systemic inflammation markers associated with heart disease

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DT Editorial Team·Mar 9, 2026·5 min read·via medicalxpress.com

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Natural Gut Compound Shows Promise for Safe Weight Loss

Researchers identify a naturally occurring gut bacterial metabolite that suppresses appetite and enhances fat metabolism
The postbiotic compound works through the gut-brain axis without the gastrointestinal side effects of current weight loss drugs
People maintaining healthy weight long-term had significantly higher circulating levels of this metabolite in a 5,000-person cohort

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DT Editorial Team·Feb 11, 2026·6 min read·via medicalxpress.com

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