Breakthrough Study Shows Dramatic Reduction in NEC
In a landmark study published in the Journal of Paediatrics and Child Health, researchers have found that donated breast milk reduces the incidence of necrotizing enterocolitis (NEC) by 38% in very premature babies. The study, led by Australian Red Cross Lifeblood in collaboration with the Australian and New Zealand Neonatal Network, is the first in Australia to examine the benefits and risks of donor milk for infants born before 32 weeks gestation.
NEC is a devastating intestinal disease that causes inflammation and tissue death in the gut, often leading to sepsis and organ failure. It is the most common cause of death among the 26,000 Australian babies born prematurely each year. The condition strikes fear into the hearts of NICU parents and clinicians alike due to its rapid progression and high mortality rate.
How Donor Milk Protects Preterm Infants
While a mother's own milk is the gold standard, many preterm infants require supplementary nutrition in the early weeks while the mother's milk supply is established. In these cases, the World Health Organization recommends donor breast milk over infant formula. The new research provides strong evidence that this practice significantly reduces NEC risk.
Lead researcher Dr. Laura Klein emphasized the importance of the findings: "Our research shows that donated breast milk is a simple intervention that can significantly reduce the risk of necrotizing enterocolitis, which causes stress and heartache for many NICU families." The study analyzed data from 15 hospitals covering 4,395 infants born at 32 weeks or less between 2018 and 2020, comparing outcomes before and after the launch of Lifeblood's milk donation service.
Lifeblood's Milk Service: A Growing Lifeline
Australian Red Cross Lifeblood established its milk donation service in 2018. At that time, approximately three-quarters of premature babies lacked access to donated breast milk. Today, the service supplies more than 4,800 liters (1,268 gallons) of donor milk annually to 45 hospitals across the country, with dedicated milk processing facilities in Sydney and Brisbane. Demand continues to grow as awareness of the benefits spreads.

Dr. Klein noted that interventions reducing NEC are critically important, especially as survival rates for extremely preterm infants improve. Each case of NEC prevented not only saves a life but also reduces the long-term complications associated with the disease, including intestinal strictures, short bowel syndrome, and neurodevelopmental delays.
Implications for Neonatal Care
The study's findings are expected to accelerate the adoption of donor milk programs in hospitals nationwide. Currently, access to donor milk varies by region, and some NICUs still rely heavily on formula for supplementation. The research provides compelling evidence that expanding donor milk availability could prevent dozens of NEC cases each year.
"Interventions that can reduce NEC are very important, particularly as we care for more extremely preterm infants," Dr. Klein added. The study also highlights the safety of donor milk, with rigorous screening and pasteurization processes ensuring that the milk is free from pathogens and contaminants.
Looking Ahead
As the evidence base grows, advocates hope that donor milk will become a standard component of neonatal care for preterm infants. The Australian Red Cross Lifeblood is working to expand its network of donors and increase supply to meet rising demand. For families like that of baby Sarah Oliver, whose photo accompanies the study, donor milk has been a literal lifeline.
The research underscores the profound impact of altruistic milk donation, often called 'liquid gold' by NICU staff. With continued support and awareness, this simple intervention has the potential to save countless lives and reduce the burden of NEC on families and healthcare systems.
This article is based on reporting by Medical Xpress. Read the original article.
Originally published on medicalxpress.com



