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All articles tagged with "inflammation"

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© 2026 Developments Today. All rights reserved.

inflammation Articles | Developments Today

How heart failure reshapes bone marrow to create inflammation-related immune memory

Heart Failure May Reprogram Bone Marrow Immunity

Researchers studied how heart failure changes interactions between bone-marrow support cells and blood-forming stem cells.
Heart failure reduced an HBEGF-producing Lepr-positive stromal-cell population in mouse models.
The findings identify a possible mechanism for persistent inflammation-related immune memory in heart failure.

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DT Editorial Team·Oct 16, 2026·via medicalxpress.com

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RAD51 stabilizes neutrophil extracellular traps to compartmentalize inflammation @ScienceMagazine @VeniPap @TheCrick 🇬🇧 https://t.co/Y1nHqT3HnV (via x.com)

RAD51 Stabilizes Neutrophil Extracellular Traps to Compartmentalize Inflammation

RAD51, a DNA repair protein, is found to stabilize neutrophil extracellular traps (NETs).
Stable NETs compartmentalize inflammation, preventing collateral tissue damage.
Loss or inhibition of RAD51 leads to rapid NET degradation and spread of inflammation.
Targeting RAD51 could lead to new treatments for inflammatory diseases and cancer.

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DT Editorial Team·Aug 22, 2026·via science.org

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Tips for treating—even preventing—osteoarthritis

Managing and Preventing Osteoarthritis: Expert Tips for Healthier Joints

Osteoarthritis affects over 30 million U.S. adults, commonly in the knee.
Risk factors include weak leg muscles, obesity, female gender, age, prior knee injury, and family history.
Dietary changes, such as eating more plants and less processed food, can reduce inflammation and pain.
Strengthening thigh muscles and using knee braces are common treatments.

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DT Editorial Team·Aug 19, 2026·via medicalxpress.com

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Alzheimer’s breakthrough: Scientists restore two hours of sleep without clearing brain plaques

Alzheimer’s study links sleep loss to brain immune cells

Researchers linked Alzheimer’s-related sleep loss in mice to inflammatory microglia rather than plaques alone.
Temporarily removing most microglia restored more than two hours of sleep per day.
The work points to immune modulation as a possible therapeutic direction, but it remains preclinical.

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DT Editorial Team·Jul 21, 2026·via sciencedaily.com

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Oyster meat may provide a sustainable solution for intestinal inflammation

Oyster Meat Extract Shows Promise for Treating Intestinal Inflammation

Oyster meat extract reduces inflammation in human intestinal cells.
Pacific oysters are sustainable and widely farmed.
Dried oyster meat could be a natural dietary supplement for leaky gut and chronic inflammation.

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DT Editorial Team·Jul 7, 2026·via medicalxpress.com

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Dynamic protein behavior drives blood-brain barrier specialization, study reveals

Dynamic Protein Turnover Drives Blood-Brain Barrier Specialization

IBEC-led study reveals that blood-brain barrier specialization is driven by dynamic protein turnover (ETOR) rather than just protein presence.
Nearly 1,000 membrane proteins were tracked in rat endothelial cells using advanced proteomics.
Inflammatory conditions disrupt the ETOR profile, potentially compromising BBB integrity.
Findings may lead to new therapeutic strategies for neurovascular health.

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DT Editorial Team·Jul 2, 2026·via medicalxpress.com

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Researchers discover new driver of asthma-related inflammation

Asthma Study Identifies CBX7 as a New Inflammation Driver

Researchers identified CBX7 as a newly recognized driver of allergic asthma inflammation.
The protein appears to act both in the cytoplasm and nucleus to sustain cytokine production.
Reducing CBX7 activity lowered inflammatory cytokine output in immune cells.
The findings point to a possible future therapeutic target, but not an immediate treatment.

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DT Editorial Team·Jun 26, 2026·via medicalxpress.com

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Heart Disease Treatment Shifts Toward Inflammation

Inflammation is emerging as a measurable driver of cardiovascular risk beyond cholesterol alone.
AI-enhanced coronary imaging may identify patients facing sharply higher chances of later heart attacks or death.
The shift could support more tailored use of immune-targeting therapies alongside standard lipid treatment.

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DT Editorial Team·Jun 6, 2026·via nature.com

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Pilot trial points to immune-targeted therapy for hard-to-treat depression

A 30-person pilot trial tested tocilizumab in moderate-to-severe depression that had not responded to standard antidepressants.
Compared with placebo, the anti-inflammatory drug appeared to reduce depression symptoms and improve fatigue, anxiety, and quality of life.
The study adds clinical support to the idea that an IL-6-linked inflammatory pathway may drive a subset of depression cases.

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DT Editorial Team·May 20, 2026·via medicalxpress.com

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Researchers overturn a 30-year theory of a rare inflammatory disease

A study in Immunity says natural killer cells are impaired in MKD and may drive inflammatory flares.
The finding challenges a 30-year emphasis on macrophages as the main culprit.
Researchers say JAK inhibitors or other interferon gamma-targeting drugs should now be explored clinically.

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DT Editorial Team·Apr 30, 2026·via medicalxpress.com

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Harvard scientists link gut bacteria to depression through hidden inflammation trigger

Harvard Researchers Trace a Possible Gut-to-Depression Path Through an Inflammation Trigger

Researchers identified a mechanism involving Morganella morganii and the contaminant DEA.
The altered bacterial molecule triggers immune activity and inflammatory cytokines.
The findings may open paths to diagnosis or treatment that target immune pathways.

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DT Editorial Team·Apr 25, 2026·via sciencedaily.com

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Rare T Cells Implicated in Inflammatory Cascade Behind Liver Fibrosis

A Julius Maximilian University of Wurzburg study examined immune cell networks in liver disease.
The study links a rare T cell type to signaling that amplifies inflammation.
The inflammatory cascade is reported to contribute to liver fibrosis.
The supplied source text supports a mechanistic finding, not a new treatment.

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DT Editorial Team·Apr 21, 2026·via medicalxpress.com

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Early Arthritis Study Puts PEPITEM Forward as a Potential New Therapy Class

Researchers say PEPITEM reduced arthritic joint swelling and inflammation.
The effect is described as comparable to the current standard of care.
The work points to a possible replacement-therapy approach for early-stage inflammatory arthritis.

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DT Editorial Team·Apr 13, 2026·via medicalxpress.com

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Researchers Map a Clotting and Inflammation Receptor in a Step Toward New Drug Design

Scientists created a molecular map of a human receptor involved in clotting and inflammation.
The work could help guide better drug design.
Potential applications mentioned include heart and lung diseases.

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DT Editorial Team·Apr 8, 2026·via medicalxpress.com

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Healthy Gum Tissue May Fight Disease With Mechanics, Not Just Immunity

The study links healthy gum tissue rigidity to protection against chronic periodontal inflammation.
Periodontitis can lead to tooth loss and destruction of supporting bone.
The work suggests tissue mechanics may matter alongside microbial and immune factors.

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DT Editorial Team·Apr 2, 2026·via medicalxpress.com

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woman laying on her bed holding a hot water bottle to her stomach

Study Recasts Endometriosis as a Whole-Body Immune Disorder, Not Only a Pelvic Disease

Researchers say endometriosis drives a whole-body immune response through inflammation.
The condition affects about 10% of women worldwide.
The systemic view could reshape diagnosis and treatment priorities.

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DT Editorial Team·Mar 30, 2026·via livescience.com

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Scientists Crack the Skin's Hidden Immune Alarm System

Chinese researchers mapped the complete signaling pathway by which skin keratinocytes convert local damage into body-wide immune alerts via cytokine release
The pathway is implicated in psoriasis, eczema, and contact dermatitis — conditions caused by excessive or misdirected keratinocyte alarm activation
Targeting the pathway upstream of currently treated cytokines could enable more precise inflammatory disease interventions

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DT Editorial Team·Mar 23, 2026·via medicalxpress.com

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