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NIH-backed research identifies a brain signaling pathway that could extend and strengthen semaglutide’s weight-loss эфф
Key Takeaways
- Researchers linked semaglutide’s effect to cAMP signaling in area postrema neurons.
- Some neurons sustain the response while others quickly lose it, which may help explain plateaus.
- A PDE4 inhibitor, roflumilast, appeared to restore signaling in the mouse-model study.
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DT Editorial Team··via refractor.io
