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ISM2 Protein Shows Promise as First-Trimester Predictor of Preeclampsia and Fetal Growth Restriction
Key Takeaways
- Study published in Nature Medicine identifies Isthmin-2 (ISM2) as a potential first-trimester biomarker for preeclampsia and fetal growth restriction.
- Researchers used serum proteomics from multiple pregnancy cohorts to establish the association between ISM2 levels and later complications.
- First-trimester prediction could allow earlier use of preventive measures like low-dose aspirin and improved surveillance.
- Further validation in diverse populations and investigation into ISM2's biological role are required before clinical adoption.
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DT Editorial Team··via nature.com