cell therapy Articles | Developments Today

First-in-human trial primes immune system to accept donor livers

A first-in-human trial at UPMC and the University of Pittsburgh suggests some living donor liver transplant recipients can be safely weaned off immunosuppressive drugs after donor-derived immune cell priming.

Key Takeaways

Researchers infused donor-derived immune cells before living donor liver transplantation.
Some recipients have stayed off immunosuppressive drugs for more than three years.

DT Editorial AI·Apr 17, 2026·via medicalxpress.com

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These lab-grown insulin cells reverse diabetes in mice and clear a major hurdle for type 1 treatment

Health

Stem Cell-Derived Insulin Cells Reverse Diabetes in Mice, Advancing Type 1 Therapy

Researchers in Sweden report a more reliable way to make insulin-producing cells from human stem cells, with transplanted cells restoring blood sugar control in diabetic mice for months.

Key Takeaways

Researchers say they can more reliably produce insulin-secreting cells from human stem cells.
The cells responded to glucose in lab tests and restored blood sugar control in diabetic mice.

DT Editorial AI·Apr 16, 2026·via medicalxpress.com

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A bold new plan could finally cure type 1 diabetes

Science

Two-Part Cell Therapy Aims to Cure Type 1 Diabetes

Researchers are pairing lab-grown insulin cells with engineered immune bodyguards that prevent rejection — potentially eliminating the need for lifelong immunosuppression.

Key Takeaways

Combines stem cell-derived beta cells with CAR-engineered immune bodyguards
Preclinical protection lasted one month in humanized mouse models

DT Editorial AI·Mar 2, 2026·4 min read·via sciencedaily.com

Early liver transplant trial hints at a future with less lifelong immunosuppression

Key Takeaways

Researchers infused donor-derived immune cells before living donor liver transplantation.
Some recipients have stayed off immunosuppressive drugs for more than three years.

DT Editorial AI·Apr 17, 2026·via medicalxpress.com

More in Health →

Health

Stem Cell-Derived Insulin Cells Reverse Diabetes in Mice, Advancing Type 1 Therapy

Researchers in Sweden report a more reliable way to make insulin-producing cells from human stem cells, with transplanted cells restoring blood sugar control in diabetic mice for months.

Key Takeaways

Researchers say they can more reliably produce insulin-secreting cells from human stem cells.
The cells responded to glucose in lab tests and restored blood sugar control in diabetic mice.

DT Editorial AI·Apr 16, 2026·via medicalxpress.com

More in Health →

Science

Two-Part Cell Therapy Aims to Cure Type 1 Diabetes

Researchers are pairing lab-grown insulin cells with engineered immune bodyguards that prevent rejection — potentially eliminating the need for lifelong immunosuppression.

Key Takeaways

Combines stem cell-derived beta cells with CAR-engineered immune bodyguards
Preclinical protection lasted one month in humanized mouse models

DT Editorial AI·Mar 2, 2026·4 min read·via sciencedaily.com

#cell therapy

Early liver transplant trial hints at a future with less lifelong immunosuppression

Stem Cell-Derived Insulin Cells Reverse Diabetes in Mice, Advancing Type 1 Therapy

Two-Part Cell Therapy Aims to Cure Type 1 Diabetes

Early liver transplant trial hints at a future with less lifelong immunosuppression

Stem Cell-Derived Insulin Cells Reverse Diabetes in Mice, Advancing Type 1 Therapy

Two-Part Cell Therapy Aims to Cure Type 1 Diabetes