#cell therapy

A clinical trial suggests macrophage-based cell therapy could meaningfully improve four-year transplant-free survival for patients with advanced cirrhosis, offering a potential alternative to liver transplantation for a病

A Rutgers study points to senescent CD8+ T cells as a key reason some CAR T treatments fail, suggesting that the quality of the starting immune cells may shape whether the therapy can expand, persist, and work.

Researchers report a way to use engineered red blood cells to ferry mRNA into the body and reprogram myeloid immune cells to attack tumors, pointing to a potential alternative to conventional CAR cell manufacturing.

A single infusion of ciltacabtagene autoleucel reportedly produced a 100% MRD-negativity rate in patients with high-risk smoldering multiple myeloma, an outcome that could intensify discussion around how early advanced c

A first-in-human trial at UPMC and the University of Pittsburgh suggests some living donor liver transplant recipients can be safely weaned off immunosuppressive drugs after donor-derived immune cell priming.

Researchers in Sweden report a more reliable way to make insulin-producing cells from human stem cells, with transplanted cells restoring blood sugar control in diabetic mice for months.

Researchers are pairing lab-grown insulin cells with engineered immune bodyguards that prevent rejection — potentially eliminating the need for lifelong immunosuppression.