#drug discovery

A compact biotech update from Endpoints captures two recurring pressures on the sector at once: the need to keep capital flowing and the need to produce clinical evidence that can justify it.

A large Pacific coral survey reconstructed hundreds of microbial genomes, most previously undescribed, and found an unusually rich reservoir of genes linked to natural compounds that could matter for medicine and biotech

Researchers studying an Atlantic Forest tree in Brazil say leaf compounds from Copaifera lucens neutralized Covid-19 in lab testing by binding to multiple viral targets, a mechanism that could make resistance harder to发展

Researchers used two IBM quantum computers and two major supercomputers to model a 12,635-atom molecule, a new record that underscores the promise of hybrid quantum-classical chemistry.

Researchers at Linköping University say they have shown how two important cancer-related proteins can be stopped from collaborating, opening a path toward future medicines for neuroblastoma.

OpenAI has introduced GPT-Rosalind, a purpose-built reasoning model for life sciences research, aiming to support tasks from genomics and protein work to hypothesis generation and early drug discovery

New neuron-level mapping work highlights how pain-sensing cells are organized, offering a clearer starting point for future chronic inflammatory pain therapies.

Scientists have created a molecular map of a human receptor involved in blood clotting and inflammation, a finding that could support better drug development for heart and lung diseases.

Rockefeller University researchers built MultiQ-IT, a mass spectrometry device that processes billions of molecules in parallel, achieving 100-fold better sensitivity and potentially transforming drug discovery.

AI models are evolving from research assistants into genuine scientific co-investigators, with hypotheses now being validated in organoids, animal models, and early-stage clinical trials, according to Nature Medicine.

Indiana University researchers discovered that age-related blood mutations may drive severe inflammatory bowel disease, identifying a potential new drug target for Crohn's and colitis.

Researchers have pinpointed a molecular weak spot in anti-NMDA receptor encephalitis, the devastating autoimmune condition known as 'Brain on Fire.' The discovery opens the door to targeted therapies for a disease that attacks memory and cognition, causing psychiatric symptoms, seizures, and death.