#preventive medicine

An 'off-the-shelf' neoantigen vaccine has demonstrated safety and immunogenicity in individuals with Lynch syndrome, a hereditary condition that dramatically increases cancer risk. The results advance the prospect of preventive cancer vaccines for people with genetic predispositions.

Researchers at Örebro University have identified anti-integrin αvβ6 antibodies in blood samples that can flag individuals at risk of developing ulcerative colitis long before any symptoms manifest. The discovery could enable earlier interventions and potentially delay the onset of this debilitating inflammatory bowel disease.

With over 600 million people affected globally, osteoarthritis is increasingly diagnosed in younger, active individuals. Researchers are developing blood-based infrared spectroscopy tests to catch it before joint damage begins.