#preclinical research

All articles tagged with "preclinical research"

P33 reduced amyloid-beta release in cultured mouse neurons.
In an Alzheimer’s mouse model, eight weeks of treatment reduced plaque-covered brain area by 35.6%.
The work is preclinical and has not established a benefit in people.

DT Editorial Team·Oct 17, 2026·via medicalxpress.com

A Nature Medicine Perspective published online 25 September 2026 argues that sex differences should be central to cardiovascular medicine rather than a secondary consideration.
The article connects evidence across preclinical and clinical domains, framing them as complementary rather than separate literatures.
It calls for a deeper understanding of sex differences and for research, trials and translation to be redesigned around them.
The piece is a Perspective — an argument and synthesis rather than a report of new experimental data.

DT Editorial Team·Sep 27, 2026·via nature.com

Researchers used mouse models of chronic pain to test alternate-day fasting over 38 days.
Fasting was associated with lower pain sensitivity and, in one model, less anxiety-like behavior.
The study also found gut microbe changes, stronger gut barrier signs, and reduced neuroinflammation.
The findings are promising for mechanism research but remain far from clinical proof in humans.

DT Editorial Team·Aug 26, 2026·via newatlas.com

Endpoints News says in vivo CAR-T was a major theme at the ASGCT annual meeting in Boston.
The same report stresses that the work is still preclinical.
The contrast between conference buzz and early-stage evidence is the main reason the story matters.

DT Editorial Team·May 16, 2026·via endpoints.news