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RAD51 Stabilizes Neutrophil Extracellular Traps to Compartmentalize Inflammation
Key Takeaways
- RAD51, a DNA repair protein, is found to stabilize neutrophil extracellular traps (NETs).
- Stable NETs compartmentalize inflammation, preventing collateral tissue damage.
- Loss or inhibition of RAD51 leads to rapid NET degradation and spread of inflammation.
- Targeting RAD51 could lead to new treatments for inflammatory diseases and cancer.
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DT Editorial Team··via science.org