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Multiomics Profiling of Pig Liver Cross-Circulation in Human Decedents
Key Takeaways
- Longitudinal multiomics profiling of gene-edited pig liver xenografts in four human decedents.
- Pig livers showed metabolic functionality, synthesizing human proteins and clearing waste.
- Immune responses included transient complement activation and delayed innate inflammation.
- Transcriptomic data revealed adaptive gene expression changes in pig liver and human cells.
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DT Editorial Team··via nature.com