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New Mechanism Could Predict and Improve Macrophage-Targeted Cancer Immunotherapy
Key Takeaways
- Macrophage-targeted immunotherapy requires functional TLR9 receptors to be effective.
- Without TLR9, macrophages remain immunosuppressive and treatment fails.
- Combining immunotherapy with TLR9 activators enhances treatment effect.
- Human tumor data shows correlation between MARCO and TLR9 expression, suggesting clinical relevance.
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DT Editorial Team··via medicalxpress.com