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Claudin-4 Identified as Entry Point for Gut Bacterial Toxin
Key Takeaways
- Researchers identified claudin-4 as the receptor required for BFT to attach to colon cells.
- Certain B. fragilis strains produce BFT, which can damage the colon lining and promote inflammation.
- A molecular decoy protected mice from the toxin's harmful effects in preclinical testing.
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DT Editorial Team··via sciencedaily.com