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Sex and Gender Differences Belong in Treatment Guidelines, Nature Medicine Argues
Key Takeaways
- A Nature Medicine commentary published 23 September 2026 argues that sex and gender differences belong in clinical treatment guidelines.
- The piece says guidelines should state what is already known, identify where evidence is missing, and specify what future trials must report.
- Sex and gender are distinct concepts, and conflating them obscures whether observed differences arise from biology, care patterns or both.
- The commentary frames guideline writing and trial reporting as connected problems, since panels can only work with the evidence trials produce.
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DT Editorial Team··via nature.com