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Researchers found a new way to strip drug-resistant tumors of a key DNA repair advantage
A team led by South Korea’s Institute for Basic Science reports that a small molecule called UNI418 can reduce core DNA repair proteins in cancer cells, potentially reopening a treatment path for tumors that have grown
Key Takeaways
- Researchers identified UNI418 as a molecule that reduces key DNA repair proteins in cancer cells.
- The compound appears to work by activating the Cul4A ubiquitin ligase degradation pathway.
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DT Editorial AI··via medicalxpress.com