#inflammation

A small randomized trial suggests the anti-inflammatory drug tocilizumab may ease symptoms in people with moderate-to-severe depression who have not improved on standard antidepressants, adding fresh weight to the idea a

A study in Immunity points to malfunctioning natural killer cells, not macrophages alone, as a key driver of mevalonate kinase deficiency, opening a possible path toward JAK inhibitor treatment.

A Harvard Medical School team reports that Morganella morganii can produce an inflammation-triggering molecule when it interacts with an environmental contaminant, offering a clearer mechanism linking the gut microbiome,

A Julius Maximilian University of Wurzburg study reports that a rare type of T cell can trigger signaling that amplifies inflammation and contributes to liver fibrosis.

Researchers say the naturally occurring immunopeptide PEPITEM reduced joint swelling and inflammation in early-stage inflammatory arthritis to a degree comparable with current standard care.

Scientists have created a molecular map of a human receptor involved in blood clotting and inflammation, a finding that could support better drug development for heart and lung diseases.

Researchers report that the physical rigidity of healthy gum tissue helps protect against chronic periodontal inflammation, adding a mechanical dimension to how gum disease may begin and spread.

Researchers argue that endometriosis should be understood as a condition that drives immune disruption across the body, widening the frame beyond lesions in the pelvis alone.

A Chinese research team has uncovered the signaling pathway through which keratinocytes in the skin's outer layer detect local damage and broadcast systemic immune alerts — resolving a long-standing mystery about how local threats become body-wide responses.