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Blood Protein Clues May Flag Children at Risk of Cardiometabolic Disease
Key Takeaways
- Researchers from Vanderbilt Health, UTHealth Houston and UNC Chapel Hill identified early signs of cardiovascular-kidney-metabolic disease (CKMD) in children as young as 8.
- The study analyzed 273 children and adolescents in the Border Health Research Cohort in Cameron County, Texas; more than a third showed disease-associated phenotypes.
- Machine-learning methods were used to define proteomic signatures linking circulating proteins to obesity, elevated blood pressure, prediabetic insulin resistance and risky lipid levels.
- Similar protein patterns appeared in 685 local adults and in more than 28,000 UK Biobank participants, suggesting the signature is not region-specific.
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DT Editorial Team··via medicalxpress.com