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All articles tagged with "psilocybin"

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The trials of translating psilocybin treatment from research to practice | Nature Medicine (via www.nature.com)

The trials of translating psilocybin treatment from research to practice

Nature Medicine published a psilocybin feasibility trial online on 21 August 2026.
The trial delivers psilocybin-assisted therapy for treatment-resistant depression within the UK health service.
The article highlights practical challenges in translating psychedelic research into routine clinical practice.
Workforce training, regulatory barriers, and facility requirements are central translation hurdles.

DE

DT Editorial Team·Aug 23, 2026·via nature.com

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Woman open curtains in a dark room (via kcl.ac.uk)

Psilocybin-Assisted Therapy Shows Promise for Treatment-Resistant Depression in NHS Trial

Randomized controlled trial in NHS England with 60 adults with treatment-resistant major depressive disorder.
Psilocybin-assisted therapy led to significant reduction in depressive symptoms compared to placebo.
No serious adverse events; safety profile acceptable.
Findings suggest feasibility of psychedelic therapy in public healthcare settings.

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DT Editorial Team·Aug 7, 2026·via nature.com

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For veterans with severe PTSD, psilocybin-assisted therapy may help

Psilocybin Therapy Shows Early PTSD Gains in Veterans

A U.S. pilot study tested psilocybin-assisted therapy in 12 veterans with severe, treatment-resistant PTSD.
Researchers reported no serious adverse events and no significant rise in suicidal ideation scores.
Nine participants were in remission one month after treatment, but larger and longer studies are still needed.

DE

DT Editorial Team·Jul 30, 2026·via medicalxpress.com

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A single dose of psilocybin eased depression symptoms for months, our study found

Psilocybin Showed Fast Antidepressant Effects in a Small Trial, but Blinding Remains a Major Problem

A randomized trial found that psilocybin reduced depression symptoms within days and outperformed placebo over the short term.
More than half of the psilocybin group no longer met depression criteria after six weeks, versus one person in the placebo group.
Most participants correctly guessed which treatment they received, highlighting a major methodological issue in psychedelic research.

DE

DT Editorial Team·May 22, 2026·via medicalxpress.com

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A Single Psilocybin Dose Appears to Reshape Brain Activity for Weeks

Researchers found that a high dose of psilocybin increased brain entropy during the acute experience.
The degree of entropy was linked to next-day reports of insight and emotional self-awareness.
Those reported insights forecasted improvements in well-being a month later.
The study was conducted in healthy volunteers and used multiple brain measurement techniques.

DE

DT Editorial Team·May 5, 2026·via medicalxpress.com

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Psilocybin is moving deeper into depression research, but the evidence still comes with limits

Researchers reviewed 15 clinical trials testing psilocybin for depression.
The analysis was published in Nature Mental Health.
The review strengthens the case for continued study while emphasizing methodological limits.
Interest is being driven in part by patients who do not benefit enough from standard treatments.

DE

DT Editorial Team·Apr 25, 2026·via medicalxpress.com

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Psychedelics Make the Brain Hallucinate Its Own Memories

Psychedelics appear to make the brain weight stored memories over real-time sensory input
Mouse study shows shift toward top-down memory-based visual processing under psychedelic compounds
Mechanism may explain why hallucinations feel personally meaningful and has implications for therapeutic protocols

DE

DT Editorial Team·Mar 15, 2026·2 min read·via medicalxpress.com

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