#kidney disease

All articles tagged with "kidney disease"

Kidney drug finerenone may help millions more patients after three major studies

Finerenone studies widen the case for kidney disease use

Three major studies suggest finerenone could help far more chronic kidney disease patients than current approvals cover, including people without diabetes.

Key Takeaways

Three studies suggest finerenone may help beyond diabetic kidney disease.
FIND-CKD reported slower kidney decline and fewer major kidney and heart outcomes.

DT Editorial Team·Jun 5, 2026·via medicalxpress.com

Constipation Drug Shows Early Promise as a Kidney Disease Treatment

Researchers in Japan report that lubiprostone helped preserve kidney function in a Phase II trial, pointing to the gut microbiome as a possible new target in chronic kidney disease.

Key Takeaways

A Phase II trial involving 150 patients found lubiprostone slowed kidney function decline in moderate CKD.
Researchers linked the effect to microbiome changes that boosted spermidine production.

DT Editorial Team·May 8, 2026·via sciencedaily.com

Kidney disease drug development is finally building a deeper bench

After years of limited treatment options, kidney disease research is moving into a more active phase, with targeted therapies ranging from immunomodulators to genetically defined drugs.

Key Takeaways

Nature Medicine says kidney disease is seeing a surge of targeted therapies after years of limited options.
The emerging pipeline includes immunomodulators and genetically defined drugs.

DT Editorial Team·May 2, 2026·via nature.com

HNF1B Study Points to Feed-Forward Loop in Kidney Disease Progression

A new Science paper reports that HNF1B integrates signals in a feed-forward loop associated with kidney disease progression, highlighting a regulatory mechanism for further study.

Key Takeaways

Science lists a new paper on HNF1B and kidney disease progression.
The title identifies a feed-forward loop as the disease-driving mechanism.

DT Editorial Team·Apr 23, 2026·via science.org