
One-Shot Gene Editing Therapy Cuts LDL Cholesterol in Early Trial
An early clinical trial suggests a single infusion of VERVE-102 can sharply lower LDL cholesterol, pointing to a possible alternative to lifelong medication.
- A Phase 1b study tested VERVE-102 in 35 adults with inherited high cholesterol or early coronary artery disease.
- At the highest dose, LDL cholesterol fell by up to 62% after a single infusion.

