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Simple Steroid Schedule Change Halves Early Deaths in Children with Leukemia in India
Key Takeaways
- Giving steroids in short bursts instead of continuously halves early treatment-related deaths in children with leukemia.
- The pulsed schedule reduced early death rates from 3.5% to 1.3% without affecting remission or survival rates.
- The ICiCle-ALL-14 trial is the first multicenter randomized pediatric oncology trial in India, involving over 3,000 children.
- Findings address disparities in childhood leukemia survival between wealthy and low- to middle-income countries.
DE
DT Editorial Team··via medicalxpress.com