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Y Chromosome Loss Could Be the First Sign of Cancer, Study Finds
Key Takeaways
- A University of Arizona-led investigation links mosaic loss of the Y chromosome to the development of carcinomas, calling it a new hallmark of pending cancer.
- About 40% of men in their 70s have tissues that have lost the Y chromosome; by their 90s the figure approaches 60%.
- The loss creates a mosaic effect, with each affected cell forming its own patch of unique tissue within the body.
- Mosaic Y loss has previously been associated with chronic kidney disease, fibrosis and an increased risk of severe COVID-19.
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DT Editorial Team··via newatlas.com