#psychedelics

A new Nature Medicine mega-analysis pooled 11 neuroimaging datasets across five psychedelics and found a common pattern of altered connectivity linking higher-order and sensory brain systems.

Otsuka is acquiring private biotech Transcend Therapeutics in a deal worth roughly $1.2 billion, extending big pharma’s interest in neuropsychiatric medicines modeled on the therapeutic promise associated with psychedel

A new study in mice suggests psychedelic compounds make the brain prioritize stored memories over real sensory input — causing perception to be driven by internal models rather than present reality.

Researchers from the University of Southern Denmark and Bern University Hospital found no evidence that the rat brain produces or stores DMT in serotonin-releasing neurons, undermining a decades-old hypothesis about the psychedelic compound's natural role in brain chemistry.