#obesity research

All articles tagged with "obesity research"

A mouse study found that low protein intake can trigger fat browning through gut microbes.
Two signaling routes, involving FXR and FGF21, were highlighted.
The work suggests therapeutic possibilities but remains far from a human-ready intervention.

DT Editorial Team·Apr 17, 2026·via refractor.io

University of Oklahoma researchers traced FGF21’s action to the hindbrain rather than the hypothalamus.
The study says the hormone works through the nucleus of the solitary tract, area postrema, and parabrachial nucleus.
FGF21 appears to drive energy burning instead of primarily reducing appetite.
The pathway is already of interest because related drugs are being tested for MASH.

DT Editorial Team·Apr 17, 2026·via sciencedaily.com

One in eight U.S. adults now takes GLP-1 medications like Ozempic or Wegovy for weight management
GLP-1 drugs activate the brain's stress response system, elevating cortisol and causing muscle loss
Patients who stop treatment experience rebound overeating driven by chronically stimulated stress hormones
Combination therapy with anti-CRH antibodies preserved muscle and maintained weight loss after drug discontinuation
Human clinical trials of the combination approach are being planned pending partnership development

DT Editorial Team·Feb 17, 2026·6 min read·via medicalxpress.com