#MASLD

All articles tagged with "MASLD"

The LITMUS study compared 30 biomarkers and test combinations in 1,590 biopsy-diagnosed MASLD patients.
TSP2 stood out as a promising single blood marker for progressive and advanced fibrosis and inflammation.
No tested method met the study threshold for diagnosing early disease without significant fibrosis.

DT Editorial Team·Nov 2, 2026·via medicalxpress.com

University of Missouri School of Medicine researchers found endurance exercise alters liver cell energy production through different molecular pathways in male and female rats.
Female rats produced more proteins tied to the Krebs cycle, while male rats chemically modified more existing proteins to trigger the cycle.
Both sexes showed improved liver health: reduced liver fat, better cholesterol use and disposal, and fewer fibrosis markers.
Male animals expelled more cholesterol from the body than females, though reasons for the divergence remain unclear.

DT Editorial Team·Oct 1, 2026·via medicalxpress.com

A Nature Medicine research briefing summarizes results from the LITMUS imaging study in MASLD.
Elastography and elastography-based composite scores showed enough accuracy to evaluate advanced fibrosis and cirrhosis.
The study found that current markers were not accurate enough to diagnose MASH without biopsy.
The findings support a more targeted role for liver biopsy rather than full replacement across all MASLD assessments.

DT Editorial Team·Aug 4, 2026·via nature.com