Science
Scientists Launch Global Effort to Map the Human Exposome
An ambitious international initiative aims to map the human exposome -- the complete catalog of environmental and chemical exposures a person encounters over a lifetime -- potentially transforming disease prevention.
Key Takeaways
- Genetics accounts for only 10-20% of disease risk; environmental exposures drive the remaining 80-90%
- The exposome encompasses all lifetime exposures including air pollution, microplastics, pesticides, and thousands of chemicals
- Advances in mass spectrometry now allow detection of thousands of compounds simultaneously from blood and urine samples
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