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Thalamic NRXN1 Signals Guide Human Cortical Progenitor Neurogenesis
Key Takeaways
- A paper in Science (Volume 393, Issue 6815, September 2026) is titled "Thalamic NRXN1-mediated input to human cortical progenitors drives excitatory neurogenesis."
- The title's claim links three elements: thalamic-origin input, the NRXN1 gene's protein product as mediator, and human cortical progenitor cells as targets.
- The stated outcome is excitatory neurogenesis — the production of the cortex's principal activating neurons.
- The finding, if confirmed, would place the thalamus inside the construction phase of cortical development rather than only its later wiring.
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DT Editorial Team··via science.org