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Natural Hormone Reversed Obesity in Mice by Activating an Unexpected Brain Circuit
Researchers at the University of Oklahoma report that FGF21 reverses obesity in mice by acting through a hindbrain circuit linked to metabolism, pointing to a pathway distinct from appetite-suppressing GLP-1 drugs.
Key Takeaways
- University of Oklahoma researchers traced FGF21’s action to the hindbrain rather than the hypothalamus.
- The study says the hormone works through the nucleus of the solitary tract, area postrema, and parabrachial nucleus.
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DT Editorial Team··via sciencedaily.com