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ANO6 finding identifies new pancreatic cancer treatment target
Key Takeaways
- Fox Chase researchers identified ANO6 as part of a cholesterol-transfer pathway in pancreatic tumors.
- Cancer-associated fibroblasts can provide cholesterol and other lipids to cancer cells through trogocytosis.
- Blocking ANO6 slowed tumor growth and reduced immune suppression in preclinical models.
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DT Editorial Team··via medicalxpress.com