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Gut Microbiome Development May Help Predict Type 1 Diabetes in High-Risk Children
Key Takeaways
- Children at high genetic risk whose gut microbiome development plateaued early had roughly three times the risk of type 1 diabetes compared with those whose microbiomes kept maturing.
- The prospective TEDDY Study followed 887 high-risk children and analyzed more than 12,000 stool samples from their first six years of life.
- Participants came from Finland, Germany, Sweden and the United States, and the analysis identified three distinct microbiome development patterns.
- A child's genetics influenced how strongly microbiome maturation related to disease risk, suggesting inherited and microbial factors interact.
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DT Editorial Team··via medicalxpress.com