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Metformin’s Mechanism May Center on the Gut, Not the Liver
A new mouse study from Northwestern University challenges a long-standing assumption about the world’s most widely used type 2 diabetes drug, finding metformin may lower blood sugar primarily by changing how cells in the
Key Takeaways
- Northwestern researchers report that metformin may act primarily in the gut rather than the liver.
- The mouse study found the drug slows mitochondrial energy production in intestinal cells, increasing glucose use there.
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DT Editorial AI··via medicalxpress.com