Vitalik Buterin on Human Agency in the AI Era

Anish Acharya and Olivia Moore speak with Pablo Palafox and Luis Paarup about the challenges of deploying AI agents in operationally complex industries. The conversation covers the evolution of voice AI, enterprise workflows, and why logistics became an early proving ground for agent-based systems. They discuss context, coordination, and execution inside large organizations, as well as the role of forward-deployed engineering, enterprise deployment, and what it takes to move AI from experimentation into production. Resources: Pablo Palafox on X: https://x.com/pablorpalafox Luis Paarup on X: https://x.com/PaarupLuis Anish Acharya on X: https://x.com/illscience Olivia Moore on X: https://x.com/omooretweets Stay Updated: Find a16z on YouTube: YouTube Find a16z on X Find a16z on LinkedIn Listen to the a16z Show on Spotify Listen to the a16z Show on Apple Podcasts Follow our host: https://twitter.com/eriktorenberg Please note that the content here is for informational purposes only; should

Don Lincoln is a particle physicist at Fermilab who has spent decades working at the frontiers of high energy physics. https://lexfridman.com/sponsors/ep497-sc CONTACT LEX: Feedback – give feedback to Lex: https://lexfridman.com/survey AMA – submit questions, videos or call-in: https://lexfridman.com/ama Hiring – join our team: https://lexfridman.com/hiring Other – other ways to get in touch: https://lexfridman.com/contact EPISODE LINKS: https://facebook.com/Dr.Don.Lincoln/ https://drdonlincoln.com/ https://bit.ly/4nHeNiF https://bit.ly/3PCIW67 https://x.com/DrDonLincoln https://amzn.to/4uYbkOZ https://shop.thegreatcourses.com/don-lincoln https://adbl.co/4wGioRV https://www.youtube.com/fermilab https://www.fnal.gov/ https://x.com/fermilab SPONSORS: Upwork: Platform for hiring freelancers. https://upwork.com/lex Larridin: Measure AI adoption in your business. https://larridin.com Fin: AI agent for customer service. https://fin.ai/lex LMNT: Zero-sugar electrolyte drink mix. https://drink

The “Hard Fork” team is taking a break this week as we prepare for our upcoming live show in San Francisco. While we’re away, we’re bringing you a recent episode of “Interesting Times” with Ross Douthat that we really enjoyed. In this episode, Ross talks with Andrew Miller, writer of the transportation policy newsletter “Changing Lanes” and co-author of the book “The End of Driving.” Together, they explore the potential benefits of driverless cars — from fewer car crashes to reclaimed time and attention — as well as what could be lost if we don’t have to be in the driver’s seat anymore. Guest: Andrew Miller, writer of the newsletter “Changing Lanes.” Additional Reading: A full transcript and video of this episode can be found here. We want to hear from you. Email us at [email protected]. Find “Hard Fork” on YouTube and TikTok. Subscribe today at nytimes.com/podcasts or on Apple Podcasts and Spotify. You can also subscribe via your favorite podcast app here https://www.nytimes.com/ac

David George, General Partner at a16z, and David Clark, CIO at VenCap, discuss how AI is reshaping venture capital and the technology industry itself. They examine why today’s AI companies are scaling faster than any previous generation of startups, and why the eventual outcomes may be significantly larger than most investors currently expect. The conversation covers frontier AI models, coding agents, open source competition, data center constraints, and who ultimately captures value in the AI ecosystem. They also discuss what these shifts mean for venture capital itself, including larger company outcomes, faster value creation, and the growing challenge of identifying durable winners in a market evolving at unprecedented speed. Resources: Follow David George on X: https://x.com/DavidGeorge83 Follow David Clark on X: https://x.com/daveclark85 Follow VenCap on X: https://www.vencap.com Stay Updated: Find a16z on YouTube: YouTube Find a16z on X Find a16z on LinkedIn Listen to the a16z Sh