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Mouse Study Links High-Fat Diets to Synapse-Related RNA Changes
Key Takeaways
- High-fat feeding reduced PQBP1 expression in the mouse study.
- The change was associated with altered splicing of genes involved in synaptic function.
- Pioglitazone and AAV-PQBP1 improved reported synaptic and cognitive outcomes in mice.
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DT Editorial Team··via medicalxpress.com