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Advanced Optical Imaging Reveals Hidden Metabolic Activity in Blood Immune Cells
Key Takeaways
- Researchers used optical metabolic imaging (OMI) to measure metabolic activity in individual immune cells within unmodified PBMC samples.
- OMI is label-free and nondestructive, relying on natural fluorescence of NADH and FAD.
- The technique can distinguish different metabolic states, providing functional insight beyond cell type identification.
- This approach could improve monitoring of immune-related diseases and guide CAR T-cell therapy development.
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DT Editorial Team··via phys.org