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'Immune Fog' May Reveal Lung Cancer Risk Years Before Tumors Form
Key Takeaways
- UCL researchers describe a gradual buildup of regulatory T cells — an "immune fog" — that appears months or years before lung cancer develops.
- Tregs normally restrain other immune cells, potentially allowing precancerous lesions to escape immune detection and become tumors.
- The team followed the signal with prototype blood tests and reversed it using drugs, suggesting a possible interception strategy.
- The study combined human blood and tissue samples from long-running lung cancer screening studies with mouse experiments.
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DT Editorial Team··via medicalxpress.com