Study examines the path from symptoms to a cancer diagnosis

Young adults diagnosed with cancer described delays in seeking medical care after first noticing symptoms and, in some cases, said their concerns were dismissed by doctors, according to research led by a University at Buffalo postdoctoral associate.

The study focuses on a period that receives less attention than prevention and treatment: the interval between a person recognizing a potentially troubling symptom and receiving a diagnosis. For people in their twenties and thirties, that interval can be shaped by assumptions that serious illness is unlikely, by pressures of work and daily life, and by the reactions they receive when they seek care.

Natasha Allard developed the work while pursuing a doctorate in community health and health behavior at the University at Buffalo. The research was published August 22 in the journal Cancer Causes & Control. Heather Orom, an associate professor in the university’s School of Public Health and Health Professions, was a co-author along with researchers affiliated with Roswell Park Comprehensive Cancer Center, Hunter College and the University at Buffalo.

Symptoms were often attributed to stress

According to the report, many young adults waited months or even years after noticing symptoms before seeing a physician. Participants often attributed physical changes to stress or other less serious explanations, a pattern that can make an appointment seem unnecessary or easy to postpone.

The research grew from Allard’s observation that cancer can profoundly disrupt the lives of younger people. Her interest was sharpened after a close friend was diagnosed with stage 4 testicular cancer at age 26. While working in marketing and communications at Roswell Park, she learned that cancer diagnoses were increasing among young adults even as rates were steady or declining in older groups.

Allard interviewed 30 people between the ages of 20 and 39 in early 2023. The study sought to understand how they decided whether symptoms were serious and how physicians responded when they did seek medical attention.

Age can shape the clinical encounter

The article describes accounts from young adults who felt that clinicians did not initially take their concerns seriously. That experience matters because a patient’s first interaction with the health-care system can either reinforce a decision to pursue answers or make a person less likely to return promptly when symptoms persist.

The findings do not establish that every delayed diagnosis is caused by dismissal, nor do they provide a universal rule for interpreting symptoms. Cancer includes many diseases, and common symptoms often have non-cancer causes. But the research highlights how age-related expectations can influence both sides of a medical encounter: patients may minimize symptoms because they see themselves as too young for cancer, while clinicians may also begin with more common explanations.

A patient undergoing a physical exam by a doctor in an exam room.
Young adults often attribute troublesome physical symptoms to stress and put off making an appointment with a physician. Credit: Douglas Levere

That makes communication central. Young adults need to feel able to describe persistent or unusual changes, ask follow-up questions and return if a problem does not resolve. Clinicians, in turn, need to consider the patient’s account without allowing age alone to close off further evaluation.

A growing public-health concern

The American Cancer Society identifies cancer as one of the five leading causes of death among adults ages 20 to 39. For young adult women, it is the leading cause of disease-related death, according to the source report.

Those figures help explain why Allard’s work is aimed at earlier attention to symptoms. Public-health messaging around cancer often emphasizes prevention, screening and treatment, all of which remain essential. The new research draws attention to another point in the pathway: what people do after they notice something wrong but before they receive a diagnosis.

Allard said that this time matters. Her work is not an argument for panic over every symptom. Instead, it suggests that young adults should not automatically treat persistent concerns as a normal consequence of stress or a problem that can indefinitely wait.

Implications for patients and providers

The study’s value lies in its patient-centered view of diagnosis. Quantitative data can show when diagnoses occur, but interviews can reveal why a person waited, what information they had, what they feared and how an earlier clinical visit affected their next decision.

For health systems, the findings point toward communication that makes younger patients feel welcome in conversations about serious disease. For clinicians, they reinforce the importance of listening to changing or persistent symptoms and explaining a plan for follow-up. For patients, they support the practical idea of paying attention to their bodies and seeking medical advice when something does not feel right.

Earlier evaluation does not guarantee a specific outcome, and the study does not replace individualized medical care. Its contribution is to show that the path to diagnosis is not purely medical. It is also shaped by confidence, expectations and whether young adults believe they will be heard.

Research opens a conversation

Allard’s study offers a focused look at a problem that can be overlooked when cancer is treated primarily as a disease of older age. As cancer affects more young adults, understanding delays before diagnosis may become increasingly important for education, clinical practice and future research.

The core message is measured but consequential: age should not prevent people from taking persistent symptoms seriously, and it should not prevent the health-care system from listening carefully when they do.

This article is based on reporting by Medical Xpress. Read the original article.

Originally published on medicalxpress.com