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How Genetic Influences on Cognition Shift from Rare to Common Variants as Children Age
Key Takeaways
- Rare DNA changes are most strongly linked to cognition in early childhood, but the link fades as children age.
- Common DNA changes show stronger links to cognition later in childhood.
- The study analyzed exome sequencing data from 6,495 children in the Children of the 90s cohort.
- Findings may explain incomplete penetrance of rare variants associated with intellectual disability.
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DT Editorial Team··via medicalxpress.com