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AI Maps Alzheimer's Phenotypes Across 584 Donor Brains
Key Takeaways
- A study in Nature Medicine applies AI to population-scale single-cell data to characterize Alzheimer's disease phenotypes.
- The cohort comprises 584 brain donors, including patients with Alzheimer's disease and a comparison group.
- The work aims to move beyond a single uniform Alzheimer's label toward distinguishable molecular phenotypes.
- Key open questions include replication in independent cohorts and translation to living-patient biomarkers.
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DT Editorial Team··via nature.com