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A Tiny Lattice Beneath Neurons May Hold the Key to Slowing Alzheimer's
Key Takeaways
- Penn State discovers the membrane-associated periodic skeleton (MPS), a lattice beneath neurons that controls amyloid-beta uptake
- When the MPS degrades, endocytosis accelerates unchecked, causing neurons to accumulate dangerous amyloid-beta levels
- Super-resolution microscopy revealed the MPS actively regulates vesicle formation, not just passive structural support
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DT Editorial Team··3 min read·via medicalxpress.com