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Study maps how semaglutide and colchicine may help stop atrial fibrillation before it starts
Key Takeaways
- Researchers studied how semaglutide and colchicine affect atrial remodeling after heart injury.
- Semaglutide reduced fibrosis and helped preserve Connexin-43 placement between heart cells.
- Colchicine blocked stress-signaling pathways including p38, JNK, and AKT.
- Both drugs suppressed the NLRP3 inflammasome, a major inflammatory driver in heart disease progression.
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DT Editorial Team··via medicalxpress.com